Skip to main content
Erschienen in:

18.11.2019 | original article

Assessing the health-related quality of life in type 2 diabetes patients treated with insulin and oral antidiabetic agents

verfasst von: Nawras Al-Taie, Delia Maftei, Alexandra Kautzky-Willer, Michael Krebs, Harald Stingl

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 5-6/2021

Einloggen, um Zugang zu erhalten

Summary

Background

Assessing the quality of life (QOL) for patients with type 2 diabetes is an essential part of diabetes management, especially for the evaluation of new antidiabetic treatments and glucose monitoring technologies. Accordingly, the aim of this study was to assess QOL according to treatment types.

Methods

This cross-sectional study included 170 patients with type 2 diabetes from the region of Melk in Lower Austria. Of the patients 61 used only oral antidiabetic agents (OAD) and 109 patients were treated with insulin (with or without OAD). The QOL was assessed in patients using sodium-glucose cotransporter 2 inhibitors (SGLT2 inhibitors). Among the 170 patients with type 2 diabetes 95 used SGLT2 inhibitors. The World Health Organization Quality of Life BREF (WHOQOL-BREF) assessment was used to assess QOL among these patients. The Mann–Whitney U-test was utilized in this study and a P value <0.05 was considered statistically significant.

Results

Regarding the 170 participants, most were male (58.82%) and the mean glycated hemoglobin (HbA1c) level was 55.46 ± 12.30 mmol/mol (7.2%). The WHOQOL-BREF scores among type 2 diabetes patients were relatively high, which reflect a good QOL and the mean physical, psychological, social and environmental domain scores were 64.53 ± 20.15, 71.29 ± 18.08, 70.10 ± 20.08, and 84.419 ± 11.22 SD, respectively. There were no statistically significant differences in WHOQOL scores of the domains between the insulin-treated group and OAD group and between the group treated with SGLT2 inhibitors and the group not treated with SGLT2 inhibitors.

Conclusion

This study showed no QOL distinctions between treatment groups in patients with type 2 diabetes; however, a large cohort study is needed to examine these groups further.
Literatur
3.
Zurück zum Zitat Davies MJ, D’Alessio DA, Fradkin J, Kernan WN, Mathieu C, Mingrone G, et al. Management of hyperglycaemia in type 2 diabetes. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care. 2018;61:2461–98. https://doi.org/10.2337/dci18-0033.CrossRef Davies MJ, D’Alessio DA, Fradkin J, Kernan WN, Mathieu C, Mingrone G, et al. Management of hyperglycaemia in type 2 diabetes. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care. 2018;61:2461–98. https://​doi.​org/​10.​2337/​dci18-0033.CrossRef
7.
Zurück zum Zitat Chambers JM, Cleveland WS, Kleiner B, and Tukey PA. (1983). Comparing Data Distributions. In Graphical Methods for Data Analysis, 62. Belmont, California: Wadsworth International Group. Chambers JM, Cleveland WS, Kleiner B, and Tukey PA. (1983). Comparing Data Distributions. In Graphical Methods for Data Analysis, 62. Belmont, California: Wadsworth International Group.
11.
Zurück zum Zitat Chaveepojnkamjorn W, Pichainarong N, Schelp FP, Mahaweerawat U. Quality of life and compliance among type 2 diabetic patients. Southeast Asian J Trop Med Public Health. 2008;39:328–34.PubMed Chaveepojnkamjorn W, Pichainarong N, Schelp FP, Mahaweerawat U. Quality of life and compliance among type 2 diabetic patients. Southeast Asian J Trop Med Public Health. 2008;39:328–34.PubMed
12.
Zurück zum Zitat Ohkubo Y, Kishikawa H, Araki E, Miyata T, Isami S, Motoyoshi S, et al. Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6‑year study. Diabetes Res Clin Pract. 1995;28:103–17. https://doi.org/10.1016/0168-8227(95)01064-K.CrossRefPubMed Ohkubo Y, Kishikawa H, Araki E, Miyata T, Isami S, Motoyoshi S, et al. Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6‑year study. Diabetes Res Clin Pract. 1995;28:103–17. https://​doi.​org/​10.​1016/​0168-8227(95)01064-K.CrossRefPubMed
17.
Zurück zum Zitat Pufal J, Gierach M, Pufal M, Bronisz A, Kiełbasa L, Junik R. The influence of socio-demographic and clinical factors on quality of life of patients with type 2 diabetes. Diabetol Kliniczna. 2004;4:137–136. kpbc.ukw.edu.pl/content/44867/020408pufal.pdf [in Polish]. Pufal J, Gierach M, Pufal M, Bronisz A, Kiełbasa L, Junik R. The influence of socio-demographic and clinical factors on quality of life of patients with type 2 diabetes. Diabetol Kliniczna. 2004;4:137–136. kpbc.ukw.edu.pl/content/44867/020408pufal.pdf [in Polish].
Metadaten
Titel
Assessing the health-related quality of life in type 2 diabetes patients treated with insulin and oral antidiabetic agents
verfasst von
Nawras Al-Taie
Delia Maftei
Alexandra Kautzky-Willer
Michael Krebs
Harald Stingl
Publikationsdatum
18.11.2019
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 5-6/2021
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-019-01573-0