Acute myeloid leukemia (AML) is the most frequent form of acute leukemia in adults. While the prognosis is still dismal for many AML patients, the recent progress in diagnostics and risk stratification combined with the emergence and approval of …

While osteosarcomas are the most common primary malignancies of bones, which mainly occur in children, adolescents, and young adults (below 24 years) [ 1 , 2 ], they are rare representing less than 1% of all malignant cancers diagnosed in the USA [ …3

Amyloid-beta (Aβ) antibody treatment has emerged as a promising approach for the treatment of Alzheimer’s disease (AD), targeting the accumulation of Aβ plaques, which are a hallmark of the disease. This review provides an update on recent …

Prostate cancer (PCa) is the second most common malignancy among men globally [ 1 ]. In Austria PCa accounts for approximately one quarter of all new malignant neoplasms diagnosed in males and is responsible for nearly one eighth of all cancer …

Peritoneal mesothelioma (PM) is a rare disease originating from the serosal layer of the peritoneum. Various subtypes can be distinguished histologically that vary according to their malignant potential [ 1 ]. While diffuse malignant peritoneal …

The development of monoclonal anti-amyloid antibodies, a disease-modifying treatment for Alzheimer’s disease (AD), has raised the necessity to identify the epidemiological profile of the possible target patients who would benefit from such …

Have you ever wondered what your subconscious mind is truly capable of? We often enter spontaneous trances, natural states that help our minds process and heal in the background. This year, we celebrate not only the 30th anniversary of the new …

Research involving human subjects or identifiable human material and data must be assessed by an ethics committee. The Karl Landsteiner University of Health Sciences has established a Commission on Ethics and Scientific Integrity to evaluate …

Chimeric antigen receptor (CAR)-T cell therapy is a new and successful treatment for otherwise refractory malignancies but despite the growing number of applications, this form of treatment is still associated with significant toxicity. Cytokine …

Multiple myeloma (MM) is a paradigmatic example of the evolving landscape of cancer treatment. With advances in therapeutic modalities, including novel targeted agents and immunotherapies, patients diagnosed with MM are now experiencing prolonged …

Colorectal deep endometriosis (DE) affects 3–20% of women of reproductive age [ 1 , 2 ]. Patients with deep endometriosis have several treatment options including surgery. This may involve partial, full-thickness discoid resection (FTDR) or …

Dementia is emerging as one of the most serious problems in care of old people. As the mean age of the population increases, the incidence and prevalence of this condition continue to steadily rise worldwide [ 1 ]. Alzheimer’s disease (AD) is the …

With approximately 1 in 2000–3000 individuals affected, neurofibromatosis type 1 (NF1) is one of the most common hereditary cancer syndromes [ 1 ]. Approximately 50% of patients inherit the disorder in an autosomal dominant way, while the remaining …

While mortality rates from advanced chronic liver disease (ACLD) are rapidly increasing, patients with an advanced disease stage have a comparable or even higher symptom burden than those with other life-limiting diseases. Although evidence is …

Shoulder pain is one major reason for primary care consultations, concerning 16–21% of the general population and with many cases remaining for years. Rotator cuff (RC) tendinopathy is one of the most prevalent causes of shoulder pain. Its …

Gastroesophageal cancer is a devastating disease with high mortality rates worldwide particularly in younger patients [ 1 ]. Moreover, the longstanding belief that the prevalence is highest in Asian patients due to lifestyle and environmental …

Spontaneous intracranial hypotension (SIH), characterized by headaches worsening in an upright position due to cerebrospinal fluid (CSF) leaks or low CSF pressure, presents diagnostic challenges due to its rarity (5 cases per 100,000 person-years) …

This article delves into the beginnings of the dissection course, a teaching practice which today is still in place in Vienna and continues to shape future medical practitioners. Based on a comparison of different historical sources the article …

Overactive bladder (OAB) syndrome is defined by the International Continence Society as urinary urgency, with or without urgency urinary incontinence (UUI), and usually accompanied by frequency and nocturia in the absence of urinary tract …