Skip to main content
Home
Zeitschriften
Zeitungen
Podcast
Gesundheitspolitik
Praxis
Allerlei
Jobs
Fachgebiete
Allgemeinmedizin Anästhesiologie & Intensivmedizin Apotheke Augenheilkunde Chirurgie Dermatologie Gynäkologie und Geburtshilfe HNO Innere Medizin Kinder & Jugendheilkunde Neurologie & Psychiatrie Orthopädie & Unfallchirurgie Pflege Urologie Zahnmedizin
Subfächer Innere Medizin
Diabetologie Gastroenterologie Infektiologie Kardiologie Onkologie und Hämatologie Pneumologie Rheumatologie
Fortbildungen
Überblick Fortbildungen DFP-Literaturstudium-Artikel DFP-Webcast Fortbildungen DFP-Podcasts
Erweiterte Suche
Anmelden
nach oben
Wiener klinische Wochenschrift
Erschienen in:

01.08.2015 | original article

Vision problems in Down syndrome adults do not hamper communication, daily living skills and socialisation

verfasst von: Anastasia Dressler, MD, Margherita Bozza, MD, Valentina Perelli, PhD, Francesca Tinelli, MD, Andrea Guzzetta, MD, Prof. Giovanni Cioni, MD, Stefania Bargagna, MD

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 15-16/2015

Einloggen, um Zugang zu erhalten

Summary

Background

Down syndrome is the most commonly occurring chromosomal condition with a prevalence of 11.2–10000 life-births in Europe. The most important concern consists of various degrees of intellectual disability and sensory deficits. The overall prevalence of ophthalmologic abnormalities has been reported to be as high as 46–100 %. Impairment of vision potentially hampers the capacity of learning and communication and thus of social integration. The aim of our study is to assess prospectively the occurrence of vision problems in patients with DS with special emphasis on adaptive behaviour and cognition.

Methods

Assessments included Hirschberg’s corneal reflex method, eye alignment, cover test, Vineland Adaptive Behaviour Scales (VABS) for adaptive behaviour and Coloured Progressive Matrices (CPM) for cognitive abilities.

Results

We included prospectively 49 individuals from 19–52 years. Ophthalmologic problems were observed in 81.6 % of our DS patients. The total number of visual disorders and symptoms was equally distributed with respect to ID-group and to levels of adaptive behaviour (p > 0.050). When comparing individuals matched for age, gender, cognitive skills and sociocultural background in a subset of individuals, vision problems did not decrease adaptive behaviour skills of our patients with visual disorders and daily living skills even fared better (p = 0.046).

Conclusions

Effective early correction and intervention on visual-motor deficits seem to be important, but nevertheless personal autonomy is not seriously detained.
Vorheriger Artikel Clostridium difficile ribotypes in Austria: a multicenter, hospital-based survey
Nächster Artikel Thyroid screening in HIV-infected patients with antiretroviral therapy
Literatur
1.
Loane M, Morris JK, Addor MC, et al. Twenty-year trends in the prevalence of Down syndrome and other trisomies in Europe: impact of maternal age and prenatal screening. Eur J Hum Genet. 2013;21:27–33.PubMedCentralCrossRefPubMed
2.
Korenberg JR, Chen XN, Schipper R, et al. Down syndrome phenotypes: the consequences of chromosomal imbalance. Proc Natl Acad Sci U S A. 1994;91:4997–5001.PubMedCentralCrossRefPubMed
3.
Goodman MJ, Brixner DI. New therapies for treating Down syndrome require quality of life measurement. Am J Med Genet. 2013;161 A:639–41.CrossRef
4.
Stancliffe RJ, Lakin KC, Larson SA, et al. Demographic characteristics, health conditions, and residential service use in adults with Down syndrome in 25 U.S. States. Intellect Dev Disabil. 2012;50:92–108.CrossRefPubMed
5.
Merrick J, Koslowe K. Refractive errors and visual anomalies in Down syndrome. Downs Syndr Res Pract. 2001;6:131–3.CrossRefPubMed
6.
Roizen NJ, Mets MB, Blondis TA. Ophthalmic disorders in children with Down syndrome. Dev Med Child Neurol. 1994;36:594–600.CrossRefPubMed
7.
Woodhouse JM, Pakeman VH, Cregg M, et al. Refractive errors in young children with Down syndrome. Optom Vis Sci. 1997;74:844–51.CrossRefPubMed
8.
Cregg M, Woodhouse JM, Pakeman VH, et al. Accommodation and refractive error in children with Down syndrome: cross-sectional and longitudinal studies. Invest Ophthalmol Vis Sci. 2001;42:55–63.PubMed
9.
Haugen OH, Hovding G. Strabismus and binocular function in children with down syndrome. A population-based, longitudinal study. Acta Ophthalmol Scand. 2001;79:133–9.CrossRefPubMed
10.
Wagner RS, Caputo AR, Reynolds RD. Nystagmus in Down’s syndrome. Ophthalmology. 1990;97:1439–44.CrossRefPubMed
11.
Woodhouse JM, Pakeman VH, Saunders KJ, et al. Visual acuity and accommodation in infants and young children with Down’s syndrome. J Intellect Disabil Res. 1996;40(Pt 1):49–55.CrossRefPubMed
12.
Courage ML, Adams RJ, Hall EJ. Contrast sensitivity in infants and children with down syndrome. Vision Res. 1997;37:1545–55.CrossRefPubMed
13.
Courage ML, Adams RJ, Reyno S, Kwa PG. Visual acuity in infants and children with Down syndrome. Dev Med Child Neurol. 1994;36:586–93.CrossRefPubMed
14.
Cioni G, Bertuccelli B, Boldrini A, et al. Correlation between visual function, neurodevelopmental outcome, and magnetic resonance imaging findings in infants with periventricular leucomalacia. Arch Dis Child Fetal Neonatal Ed. 2000;82:F134–40.PubMedCentralCrossRefPubMed
15.
Guzzetta A, Mazzotti S, Tinelli F, et al. Early assessment of visual information processing and neurological outcome in preterm infants. Neuropediatrics. 2006;37:278–85.CrossRefPubMed
16.
Prechtl HFR, Cioni G, Einspieler C, Bos AF, Ferrari F. Role of vision on early motor development: lessons from the blind. Dev Med Child Neurol. 2001;43:198–201.CrossRefPubMed
17.
Atkinson J, Anker S, Nardini M, et al. Infant vision screening predicts failures on motor and cognitive tests up to school age. Strabismus. 2002;10:187–98.CrossRefPubMed
18.
Atkinson J, Nardini M, Anker S, Braddick O, Hughes C, Rae S. Refractive errors in infancy predict reduced performance on the movement assessment battery for children at 3 1/2 and 5 1/2 years. Dev Med Child Neurol. 2005;47:243–51.CrossRefPubMed
19.
Evenhuis HM, Theunissen M, Denkers I, Verschuure H, Kemme H. Prevalence of visual and hearing impairment in a Dutch institutionalized population with intellectual disability. J Intellect Disabil Res. 2001;45:457–64.CrossRefPubMed
20.
van Splunder J, Stilma JS, Bernsen RM, Arentz TG, Evenhuis HM. Refractive errors and visual impairment in 900 adults with intellectual disabilities in the Netherlands. Acta Ophthalmol Scand. 2003;81:123–9.CrossRefPubMed
21.
van Splunder J, Stilma JS, Bernsen RM, Evenhuis HM. Prevalence of visual impairment in adults with intellectual disabilities in the Netherlands: cross-sectional study. Eye (Lond). 2006;20:1004–10.CrossRef
22.
van Splunder J, Stilma JS, Bernsen RM, Evenhuis HM. Prevalence of ocular diagnoses found on screening 1539 adults with intellectual disabilities. Ophthalmology. 2004;111:1457–63.CrossRefPubMed
23.
Krinsky-McHale SJ, Silverman W, Gordon J, Devenny DA, Oley N, Abramov I. Vision Deficits in Adults with Down Syndrome. J Appl Res Intellect Disabil. 2014 May;27(3):247–63.
24.
Rocco FJ, Cronin-Golomb A, Lai F. Alzheimer-like visual deficits in Down syndrome. Alzheimer Dis Assoc Disord. 1997;11:88–98.CrossRefPubMed
25.
Lavrich JB, Nelson LB. Diagnosis and treatment of strabismus disorders. Pediatr Clin North Am. 1993;40:737–52.PubMed
26.
Prasher V. Screening of ophthalmic pathology and its associated effects on adaptive behaviour in adults with Down’s syndrome. Eur J Psychiat. 1994;8:197–204.
27.
Evenhuis HM, Sjoukes L, Koot HM, Kooijman AC. Does visual impairment lead to additional disability in adults with intellectual disabilities?. J Intellect Disabil Res. 2009;53:19–28.CrossRefPubMed
28.
Vig S, Jedrysek E. Adaptive behavior of young urban children with developmental disabilities. Ment Retard. 1995;33:90–8.PubMed
29.
Cicchetti DV, Sparrow SS. Assessment of Adaptive behaviour in young children. In JH Johnson, J Goldman (eds), Developmental assessment in clinical child psychology: A handbook New York: Pergamon Press, Pergamon general psychology series 1990;163:173–96.
30.
Sparrow SS, Balla DA, Cicchetti DV. The Vineland Adaptive Behaviour Scales. Circle Pines MN: America Guidance Service 1984.
31.
Sparrow SS, Balla DA, Cicchetti DV, et al. Vineland adaptive behavior scales intervista, forma completa, manuale, adattamento italiano a cura di Giulia Balboni e Luigi Pedrabissi. Firenze: Os; 2003.
32.
Heber R. Modifications in the manual on terminology and classification in mental retardation. Am J Ment Defic. 1961;65:499–500.PubMed
33.
Dressler A, Perelli V, Feucht M, Bargagna S. Adaptive behaviour in Down syndrome: a cross-sectional study from childhood to adulthood. Wien Klin Wochenschr. 2010;122:673–80.CrossRefPubMed
34.
Bargagna S, Canepa G, Tinelli F. Social adjustment in children with Down mental retardation (MRD) and Fragile-X mental retardation (MRX). Panminerva Med. 2002;44:7–10.PubMed
35.
Gedye A. Dementia scale for Down syndrome: Manual. Vancouver, British Colombia Gedye Research and Consulting; 1995.
36.
Icd –10. Communicable disease report 1992;2:125.
37.
Woodhouse JM, Cregg M, Gunter HL, et al. The effect of age, size of target, and cognitive factors on accommodative responses of children with Down syndrome. Invest Ophthalmol Vis Sci. 2000;41:2479–85.PubMed
Metadaten
Titel
Vision problems in Down syndrome adults do not hamper communication, daily living skills and socialisation
verfasst von
Anastasia Dressler, MD
Margherita Bozza, MD
Valentina Perelli, PhD
Francesca Tinelli, MD
Andrea Guzzetta, MD
Prof. Giovanni Cioni, MD
Stefania Bargagna, MD
Publikationsdatum
01.08.2015
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 15-16/2015
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-015-0750-6

Weitere Artikel der Ausgabe 15-16/2015

Thyroid screening in HIV-infected patients with antiretroviral therapy

  • original article

War and peace? The oncologic and the palliative care perspective on personalized cancer treatment in a patient with advanced cancer

  • case report

Lipoprotein-apheresis: Austrian consensus on indication and performance of treatment

  • consensus report

ÖGIM FLIP

  • mitteilungen der gesellschaft

Tuberous Sclerosis Complex: new criteria for diagnostic work-up and management

  • review article

Lung cancer in pregnancy

  • case report