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Wiener Medizinische Wochenschrift
Erschienen in:

01.01.2014 | themenschwerpunkt

Alkohol induzierte kognitive Dysfunktion

verfasst von: Elisabeth Weiss, Evelin M. Singewald, PhD, Beatrix Ruepp, Josef Marksteiner

Erschienen in: Wiener Medizinische Wochenschrift | Ausgabe 1-2/2014

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Zusammenfassung

Alkoholkonsum kann zu einer akuten Intoxikation mit entsprechender klinischer Symptomatik führen. Im ersten Stadium der Alkoholintoxikation kommt es zur Exzitation mit Enthemmungen, verlängerten Reaktionszeiten und verminderter Schmerzwahrnehmung, sowie zu nachweisbaren Veränderungen der kognitiven Leistungen insbesondere zu einer Beeinträchtigung der Gedächtnisleistungen. Jedoch sind die kognitiven Folgen einer Intoxikation in den allermeisten Fällen reversibel sofern keine Alkoholabhängigkeit besteht. Durch chronischen Alkoholkonsum ergeben sich erhebliche neuropsychologische Defizite. Insbesondere zeigen Alkoholkranke eine deutliche Dysfunktionalität in der sozialen Kognition sowie Defizite in exekutiven Funktionen wie in Problemlösefähigkeiten und Abstraktion, beim Entscheidungstreffen, Planen und Organisieren aber auch Beeinträchtigung der Handlungskontrolle und Inhibierung.
Bei etwa 50 % der Alkoholabhängigen sind Einbußen der Kognition mit einer zerebralen Atrophie in der Bildgebung des Gehirns vergesellschaftet. Es zeigen sich auch geschlechtsspezifische Unterschiede, sowohl auf akute Alkoholintoxikation, als auch bei chronischem Alkoholkonsum reagieren Frauen vulnerabler mit Entwicklung dauerhafter Schäden.
Vorheriger Artikel Management bei schwerer alkoholischer Hepatitis
Nächster Artikel Alcohol and bone
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Metadaten
Titel
Alkohol induzierte kognitive Dysfunktion
verfasst von
Elisabeth Weiss
Evelin M. Singewald, PhD
Beatrix Ruepp
Josef Marksteiner
Publikationsdatum
01.01.2014
Verlag
Springer Vienna
Erschienen in
Wiener Medizinische Wochenschrift / Ausgabe 1-2/2014
Print ISSN: 0043-5341
Elektronische ISSN: 1563-258X
DOI
https://doi.org/10.1007/s10354-013-0226-0

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