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Wiener klinische Wochenschrift
Erschienen in:

03.08.2017 | original article

Association between high cytomegalovirus antibody titers and blood pressure in the adult Kazakh and Han Chinese populations

verfasst von: Na Tang, Jia-Wei Li, Yong-Min Liu, Hua Zhong, La-Mei Wang, Feng-Mei Deng, Jing Hui, Yuan-Yuan Qu, Fang He

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 19-20/2017

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Summary Background Material and methods Results Conclusion

Human cytomegalovirus (CMV) has been linked to the pathogenesis of elevated arterial blood pressure (BP). Our study aimed to determine the association between anti-CMV titers and arterial BP in the Kazakh and Han Chinese populations.
Kazakh and Han (n = 800 each) (age, ≥18 years) subjects from Xinjiang, China were examined for anti-CMV immunoglobulin (Ig)G titers using a commercially available enzyme-linked immunosorbent assay (ELISA) kit. The highest anti-CMV titer tertiles determined within gender and ethnicity groups were compared against the two lower tertiles and seronegative samples.
Multivariate linear regression analysis revealed that anti-CMV titers were independent determinants for elevated systolic (p = 0.006) BP in Kazakh women and inversely associated with systolic (p = 0.004) and mean arterial (p = 0.019) BP in Han women.
The association between CMV infection and/or resulting immune response and BP elevation differed by sex and ethnicity. In Kazakh women, they were associated with elevated BP and the opposite was true among Han women.
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Metadaten
Titel
Association between high cytomegalovirus antibody titers and blood pressure in the adult Kazakh and Han Chinese populations
verfasst von
Na Tang
Jia-Wei Li
Yong-Min Liu
Hua Zhong
La-Mei Wang
Feng-Mei Deng
Jing Hui
Yuan-Yuan Qu
Fang He
Publikationsdatum
03.08.2017
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 19-20/2017
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-017-1239-2

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