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memo - Magazine of European Medical Oncology
Erschienen in:

01.02.2014 | short review

Multi-gene signatures in breast cancer: actual clinical impact

verfasst von: Simon P. Gampenrieder, MD, Gabriel Rinnerthaler, MD, Richard Greil, MD

Erschienen in: memo - Magazine of European Medical Oncology | Ausgabe 1/2014

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Abstract

The molecular pathology has fundamentally modified our understanding of breast cancer. Today, breast cancer is understood as a heterogeneous disease consisting of at least five different subtypes. These subtypes show specific mRNA levels and somatic alterations and derive probably from different precursor cells. Multi-gene signatures enable us not only to differentiate these subtypes but also to define different risk groups for relapse after primary treatment. The clinical impact of these signatures is critically discussed in this review.
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Nächster Artikel Breast cancer surveillance: nothing has changed in the past decades (?)
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Metadaten
Titel
Multi-gene signatures in breast cancer: actual clinical impact
verfasst von
Simon P. Gampenrieder, MD
Gabriel Rinnerthaler, MD
Richard Greil, MD
Publikationsdatum
01.02.2014
Verlag
Springer Vienna
Erschienen in
memo - Magazine of European Medical Oncology / Ausgabe 1/2014
Print ISSN: 1865-5041
Elektronische ISSN: 1865-5076
DOI
https://doi.org/10.1007/s12254-014-0130-3

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