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Journal für Endokrinologie, Diabetologie und Stoffwechsel
Erschienen in:

12.08.2021 | Originalien

Pregnancy outcome in PCOS patients: The effects of letrozol combined with exercise

verfasst von: Golshan Manteghi, Associate professor Zahra Shahraki, Maryam Nakhaie Moghadam, Assistant professor Mohammad Hosein Ghanbarpour

Erschienen in: Journal für Endokrinologie, Diabetologie und Stoffwechsel | Ausgabe 3/2021

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Abstract

Introduction

The present study is an attempt to compare the effects of letrozole therapy plus monitored exercise and letrozole therapy alone on pregnancy outcomes in infertile patients with polycystic ovary syndrome (PCOS).

Method

A total of 120 infertile women aged between 18 and 40 years with PCOS participated in this study. The patients were divided to two groups: treatment with letrozole and exercise workouts (Group 1) and treatment with letrozole only (Group 2). All data were analyzed using SPSS 22 software.

Results

The group of women that received exercise had more live births than the group of women that received only letrozole, but this difference was not significant. Biochemical pregnancy rates in Group 1 were significantly lower than Group 2 (p-value < 0.001). The number of follicles and clinical pregnancies was significantly higher in Group 1.

Conclusion

Despite the well-proven benefits of exercise for the general population and the fact that it is recommended as a basis for PCOS management, few completely controlled studies have evaluated the impact of exercise on PCOS. The present study results revealed that regular exercise combined with letrozole therapy would lead to better pregnancy outcomes in women with PCOS compared to letrozole alone.
Vorheriger Artikel Neuroendokrine Regulation des menschlichen Energiestoffwechsels
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Metadaten
Titel
Pregnancy outcome in PCOS patients: The effects of letrozol combined with exercise
verfasst von
Golshan Manteghi
Associate professor Zahra Shahraki
Maryam Nakhaie Moghadam
Assistant professor Mohammad Hosein Ghanbarpour
Publikationsdatum
12.08.2021
Verlag
Springer Vienna
Erschienen in
Journal für Endokrinologie, Diabetologie und Stoffwechsel / Ausgabe 3/2021
Print ISSN: 3004-8915
Elektronische ISSN: 3004-8923
DOI
https://doi.org/10.1007/s41969-021-00142-z

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